diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index 47d9a6a..2854627 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -53,7 +53,7 @@
             os: macos-11
     runs-on: ${{ matrix.os }}
     env:
-      NODE_LABELS: OSX
+      NODE_LABELS: macos
       WAF_JOBS: 3
     steps:
       - name: Set up Xcode
diff --git a/.github/workflows/docs.yml b/.github/workflows/docs.yml
index f27285b..19f1f82 100644
--- a/.github/workflows/docs.yml
+++ b/.github/workflows/docs.yml
@@ -26,7 +26,7 @@
         run: |
           case ${RUNNER_OS} in
             Linux) export NODE_LABELS="Linux Ubuntu" ;;
-            macOS) export NODE_LABELS="OSX" ;;
+            macOS) export NODE_LABELS="macos" ;;
           esac
           find .jenkins.d/ -type f -name '[1-9]*.sh' -exec chmod -x '{}' +
           ./.jenkins
diff --git a/.jenkins b/.jenkins
index da10d69..a9abf6d 100755
--- a/.jenkins
+++ b/.jenkins
@@ -4,6 +4,8 @@
 
 if has Linux $NODE_LABELS; then
     export PATH="${HOME}/.local/bin${PATH:+:}${PATH}"
+elif [[ -x /opt/homebrew/bin/brew ]]; then
+    eval "$(/opt/homebrew/bin/brew shellenv)"
 fi
 export CACHE_DIR=${CACHE_DIR:-/tmp}
 export WAF_JOBS=${WAF_JOBS:-1}
diff --git a/.jenkins.d/00-deps.sh b/.jenkins.d/00-deps.sh
index d3b16f9..7f56844 100755
--- a/.jenkins.d/00-deps.sh
+++ b/.jenkins.d/00-deps.sh
@@ -1,7 +1,7 @@
 #!/usr/bin/env bash
 set -ex
 
-if has OSX $NODE_LABELS; then
+if has macos $NODE_LABELS; then
     FORMULAE=(boost openssl pkg-config)
     if [[ $JOB_NAME == *"Docs" ]]; then
         FORMULAE+=(doxygen graphviz)
diff --git a/.jenkins.d/10-build.sh b/.jenkins.d/10-build.sh
index a4e6cd5..f703092 100755
--- a/.jenkins.d/10-build.sh
+++ b/.jenkins.d/10-build.sh
@@ -10,6 +10,9 @@
 if [[ $JOB_NAME == *"code-coverage" ]]; then
     COVERAGE="--with-coverage"
 fi
+if has macos-12 $NODE_LABELS; then
+    KEYCHAIN="--without-osx-keychain"
+fi
 if [[ -n $DISABLE_PCH ]]; then
     PCH="--without-pch"
 fi
@@ -31,7 +34,7 @@
 fi
 
 # Build shared library in debug mode with tests and examples
-./waf --color=yes configure --disable-static --enable-shared --debug --with-tests --with-examples $ASAN $COVERAGE $PCH
+./waf --color=yes configure --disable-static --enable-shared --debug --with-tests --with-examples $ASAN $COVERAGE $KEYCHAIN $PCH
 ./waf --color=yes build -j$WAF_JOBS
 
 # (tests will be run against the debug version)
diff --git a/.jenkins.d/20-tests.sh b/.jenkins.d/20-tests.sh
index d34fd88..abd520a 100755
--- a/.jenkins.d/20-tests.sh
+++ b/.jenkins.d/20-tests.sh
@@ -4,7 +4,7 @@
 # Prepare environment
 rm -rf ~/.ndn
 
-if has OSX $NODE_LABELS; then
+if has macos-10.15 $NODE_LABELS; then
     security unlock-keychain -p named-data
 fi
 
diff --git a/.jenkins.d/README.md b/.jenkins.d/README.md
index e8dbf37..d382757 100644
--- a/.jenkins.d/README.md
+++ b/.jenkins.d/README.md
@@ -1,6 +1,6 @@
-# CONTINUOUS INTEGRATION SCRIPTS
+# Continuous Integration Scripts
 
-## Environment Variables Used in Build Scripts
+## Environment Variables
 
 - `NODE_LABELS`: space-separated list of platform properties. The included values are used by
   the build scripts to select the proper behavior for different operating systems and versions.
@@ -9,9 +9,9 @@
 
   Example values:
 
-  - `[OS_TYPE]`: `Linux`, `OSX`
+  - `[OS_TYPE]`: `Linux`, `macos`
   - `[DISTRO_TYPE]`: `Ubuntu`, `CentOS`
-  - `[DISTRO_VERSION]`: `Ubuntu-16.04`, `Ubuntu-18.04`, `CentOS-8`, `OSX-10.14`, `OSX-10.15`
+  - `[DISTRO_VERSION]`: `ubuntu-20.04`, `ubuntu-22.04`, `centos-9`, `macos-10.15`, `macos-11`
 
 - `JOB_NAME`: optional variable that defines the type of build job. Depending on the job type,
   the build scripts can perform different tasks.
diff --git a/.waf-tools/boost.py b/.waf-tools/boost.py
index 4b2ede5..a6cdabe 100644
--- a/.waf-tools/boost.py
+++ b/.waf-tools/boost.py
@@ -54,8 +54,8 @@
 from waflib.Configure import conf
 from waflib.TaskGen import feature, after_method
 
-BOOST_LIBS = ['/usr/lib', '/usr/local/lib', '/opt/local/lib', '/sw/lib', '/lib']
-BOOST_INCLUDES = ['/usr/include', '/usr/local/include', '/opt/local/include', '/sw/include']
+BOOST_LIBS = ['/usr/lib', '/usr/local/lib', '/opt/homebrew/lib', '/opt/local/lib', '/sw/lib', '/lib']
+BOOST_INCLUDES = ['/usr/include', '/usr/local/include', '/opt/homebrew/include', '/opt/local/include', '/sw/include']
 
 BOOST_VERSION_FILE = 'boost/version.hpp'
 BOOST_VERSION_CODE = '''
diff --git a/.waf-tools/default-compiler-flags.py b/.waf-tools/default-compiler-flags.py
index f086c17..78cf40d 100644
--- a/.waf-tools/default-compiler-flags.py
+++ b/.waf-tools/default-compiler-flags.py
@@ -33,7 +33,7 @@
                       'The minimum supported clang version is 6.0.')
         conf.flags = ClangFlags()
     else:
-        warnmsg = '%s compiler is unsupported' % cxx
+        warnmsg = f'{cxx} compiler is unsupported'
         conf.flags = CompilerFlags()
 
     if errmsg:
@@ -200,7 +200,8 @@
         flags = super(ClangFlags, self).getGeneralFlags(conf)
         if Utils.unversioned_sys_platform() == 'darwin':
             # Bug #4296
-            flags['CXXFLAGS'] += [['-isystem', '/usr/local/include'], # for Homebrew
+            brewdir = '/opt/homebrew' if platform.machine() == 'arm64' else '/usr/local'
+            flags['CXXFLAGS'] += [['-isystem', f'{brewdir}/include'], # for Homebrew
                                   ['-isystem', '/opt/local/include']] # for MacPorts
         elif Utils.unversioned_sys_platform() == 'freebsd':
             # Bug #4790
diff --git a/.waf-tools/openssl.py b/.waf-tools/openssl.py
index 47bda66..51521c4 100644
--- a/.waf-tools/openssl.py
+++ b/.waf-tools/openssl.py
@@ -19,8 +19,11 @@
 from waflib import Utils
 from waflib.Configure import conf
 
-OPENSSL_DIR_OSX = ['/usr/local', '/opt/local', '/usr/local/opt/openssl']
 OPENSSL_DIR = ['/usr', '/usr/local', '/opt/local', '/sw']
+OPENSSL_DIR_MACOS = ['/usr/local',
+                     '/opt/homebrew/opt/openssl', # Homebrew on arm64
+                     '/usr/local/opt/openssl',    # Homebrew on x86_64
+                     '/opt/local']                # MacPorts
 
 def options(opt):
     opt.add_option('--with-openssl', type='string', default=None, dest='openssl_dir',
@@ -43,7 +46,7 @@
 
     openssl_dirs = OPENSSL_DIR
     if Utils.unversioned_sys_platform() == 'darwin':
-        openssl_dirs = OPENSSL_DIR_OSX
+        openssl_dirs = OPENSSL_DIR_MACOS
 
     for dir in openssl_dirs:
         file = self.__openssl_get_version_file(dir)
diff --git a/docs/INSTALL.rst b/docs/INSTALL.rst
index 0393475..45652ab 100644
--- a/docs/INSTALL.rst
+++ b/docs/INSTALL.rst
@@ -7,23 +7,23 @@
 ndn-cxx is built against a continuous integration system and has been tested on the
 following platforms:
 
--  Ubuntu 18.04 (amd64, armhf, i386)
--  Ubuntu 20.04 (amd64)
--  Ubuntu 21.10 (amd64)
--  CentOS Stream 9
--  macOS 10.15
--  macOS 11 (Intel only)
+- Ubuntu 18.04
+- Ubuntu 20.04
+- Ubuntu 22.04
+- Debian 11
+- CentOS Stream 9
+- macOS 10.15
+- macOS 11
+- macOS 12
 
 ndn-cxx is known to work on the following platforms, although they are not officially
 supported:
 
--  Alpine >= 3.12
--  Debian >= 10
--  Fedora >= 29
--  Gentoo Linux
--  Raspberry Pi OS (formerly Raspbian) >= 2019-06-20
--  FreeBSD >= 12.0
--  macOS 10.14
+- Alpine >= 3.12
+- Fedora >= 29
+- Gentoo Linux
+- Raspberry Pi OS (formerly Raspbian) >= 2019-06-20
+- FreeBSD >= 12.0
 
 Prerequisites
 -------------
@@ -31,13 +31,13 @@
 Required
 ~~~~~~~~
 
--  GCC >= 7.4 or clang >= 6.0 (if you are on Linux or FreeBSD)
--  Xcode >= 11.3 or corresponding version of Command Line Tools (if you are on macOS)
--  Python >= 3.6
--  pkg-config
--  Boost >= 1.65.1
--  OpenSSL >= 1.1.1
--  SQLite 3.x
+- GCC >= 7.4 or clang >= 6.0 (if you are on Linux or FreeBSD)
+- Xcode >= 11.3 or corresponding version of Command Line Tools (if you are on macOS)
+- Python >= 3.6
+- pkg-config
+- Boost >= 1.65.1
+- OpenSSL >= 1.1.1
+- SQLite 3.x
 
 To build ndn-cxx from source, one must first install a C++ compiler and all necessary
 development tools and libraries:
@@ -83,10 +83,10 @@
 To build tutorials, man pages, and API documentation the following additional dependencies
 need to be installed:
 
--  doxygen
--  graphviz
--  sphinx >= 1.3
--  sphinxcontrib-doxylink
+- doxygen
+- graphviz
+- sphinx >= 1.3
+- sphinxcontrib-doxylink
 
 The following lists the steps to install these prerequisites on various common platforms.